POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1

<div>POU2F1 promoted GC tumor growth in vivo through TTC3-AS1. SGC7901 cells were, respectively, transfected by (1) NC, (2) POU2F1-OE, and (3) POU2F1-OE + TTC3-AS1-KD. Transfected SGC7901 cells were subcutaneously injected into the left flanks of male athymic BALB/c nude mice, and GC tumorigenesis was measured. (a) Tumor photographs in experiments end. (b) Tumor volume was detected. The expression of (c) Ki67 and (d) FN1 in GC tumor tissues was evaluated using IHC assays. All experiments were performed in triplicate. 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Journal of Oncology

fig8

Figure 8

Figure 8: POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1 