Improved Survival of Leukemic Mice Treated with Sodium Caseinate in Combination with Daunorubicin without Toxicity

Table 1

Apoptosis induction percentage of WEHI-3 cells treated with the IC₅₀ and IC₂₅ of SC, cytarabine, and daunorubicin, as well as their combinations, after 72 h of culture and evaluated with the annexin V-FITC and 7AAD technique.

Treatment	Early apoptosis	Necroapoptosis	Necrosis
0	9.49	0	0.03
SC IC25	12.15	0.37	10.75
SC IC50	64.71	2.04	3.62
Cytarabine IC25	9.41	0.37	5.51
Cytarabine IC50	46.09	1.54	12.32
Daunorubicin IC25	15.72	0.44	4.35
Daunorubicin IC50	44.71	1.83	3.98
SC : cytarabine IC25 : IC25	74.59	3.96	1.56
SC : daunorubicin IC25 : IC25	73.02	3.01	0.97
Cytarabine : daunorubicin IC25 : IC25	78.16	4.16	0.88