Research Article

Addition of Nimotuzumab to Standard TPF Regimen in Locally Advanced Head and Neck Cancer: A Single Institutional Study

Table 2

Overall analysis of study population (data are expressed in median, range, and number or percentage; PFS, progression-free survival; OS, overall survival).

VariablesNMedian PFSMedian OS value

Overall2016 months (7.2–20.6 months)38 months (32–44 months)
Anatomic site
Oral cavity12 (60%)34.5 months
Hypopharynx6 (30%)38 months
Oropharynx2 (10%)35 months

Overall response rate after induction75%
Complete response2 (10%)
Partial response13 (65%)
Stable disease2 (10%)
Progressive disease3 (15%)

Overall response rate after CRT65%
Complete response6 (30%)Not reachedNot reached
Partial response7 (35%)17.6 months34.5 months
Stable disease2 (10%)8.1 months31 months
Progressive disease5 (25%)6.7 months17 months