The Clinical Significance and Potential Molecular Mechanism of Upregulated CDC28 Protein Kinase Regulatory Subunit 1B in Osteosarcoma

Figure 5

CKS1B was found to be upregulated in proliferating osteoblastic osteosarcoma (OS) cells. (a) Uniform manifold approximation and projection (UMAP) distribution of 14 annotated cell types. (b) Violin-plot displaying distribution of CKS1B in various types of cells. CH_OS: chondroblast OS cells, Den: CD1C + CD141+ dendritic cells, Eryth: erythrocyte, Fib: fibroblasts, Mono: monocyte, MSC: mesenchymal stem cells, Mye: myeloid cells, Myob: myoblasts, NK: TILs including T and NK cells, Oc: osteoclastic cells, OS: osteoblastic OS cells, Peri: pericytes, and Pro_OS: proliferating osteoblastic OS cells.

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