Research Article
Clinicopathologic Characteristics and Outcomes of Simultaneous Multiple Primary Lung Cancer
Table 2
Histological characteristics.
| | | Overall patients, N = 336 | Same histological type, N = 297 | Different histological types, N = 39 | value |
| | Pathologic characteristics | | | | | | All adenocarcinoma | 291 (86.6) | 291 (98.0) | 0 (0) | — | | Adenocarcinoma + squamous | 26 (7.7) | 0 (0) | 26 (66.7) | — | | All squamous | 6 (1.8) | 6 (2.0) | 0 (0) | — | | Adenocarcinoma + others | 11 (3.3) | 0 (0) | 11 (28.2) | — | | Squamous + others | 2 (0.6) | 0 (0) | 2 (5.1) | — | | TNM stage | | | | <0.001 | | I A1 | 63 (18.8) | 63 (21.2) | 0 (0) | | | I A2 | 96 (28.6) | 94 (31.6) | 2 (5.1) | | | I A3 | 46 (13.7) | 42 (14.1) | 4 (10.2) | | | I B | 83 (24.7) | 78 (26.3) | 5 (12.8) | | | II A | 12 (3.6) | 9 (3.0) | 3 (7.7) | | | II B | 17 (5.1) | 9 (3.0) | 8 (20.5) | | | III A | 13 (3.9) | 2 (0.7) | 11 (28.2) | | | III B | 4 (1.2) | 0 (0) | 4 (10.2) | | | IV A | 2 (0.6) | 0 (0) | 2 (5.1) | | | Pleural invasion | 108 (32.1) | 86 (29.0) | 22 (56.4) | 0.001 | | Treatment | | | | | | Surgery timing | | | | 0.287 | | Concurrent | 262 (78.0) | 229 (77.1) | 33 (84.6) | | | Sequential | 74 (22.0) | 68 (22.9) | 6 (15.4) | | | Surgery interval, mon | 7 [4–17] | 7 [4–16] | 9 [3–17] | 0.564 | | Resect all nodules | | | | 0.263 | | Yes | 122 (36.3) | 111 (37.4) | 11 (28.2) | | | No | 214 (63.7) | 186 (62.6) | 28 (71.8) | | | Other treatments | | | | | | Chemotherapy | 135 (40.2) | 109 (36.7) | 26 (66.6) | <0.001 | | Target therapy | 11 (3.3) | 11 (3.7) | 0 (0) | 0.624 |
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Values are n (%) or median (interquartile range).
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