Hsp70 Promotes SUMO of HIF-1α and Promotes Lung Cancer Invasion and Metastasis

Figure 4

Subcutaneous tumor-bearing experiments in nude mice proved that knockdown of Hsp70 inhibits the proliferation and metastasis of lung cancer cells. (a) Pictures of nude mouse tumor. (b) Tumor growth curve of nude mice. (c) Tumor weight of nude mice. (d) HE staining of lung tissue to detect metastases (magnification 200x). (e) Ki-67 immunohistochemical staining (magnification 400x). (f) qRT-PCR detects the effect of knockdown of Hsp70 in tumor tissues on the expression of E-cadherin and Vimentin. (g) qRT-PCR detects the expression of Hsp70 in tumor tissues. .

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