BCL-2 (-938C>A), BAX (-248G>A), and HER2 Ile655Val Polymorphisms and Breast Cancer Risk in Indian Population
Table 2
Genotype distribution, allele frequency, and association analysis of BCL-2(-938C>A) polymorphism and risk of breast cancer under different genetic models.
Genotype/allele
Cases (n = 117)
Control (n = 104)
Odd ratio (95% CI)
value
CC
34 (29.05%)
30 (28.84%)
Ref
Ref
AC
56 (47.86%)
51 (49.03%)
0.968 (0.521–1.801)
0.920
AA
27(23.07%)
23 (22.11%)
1.035(0.493–2.175)
0.925
value 0.980
Recessive model
AA
27
23
1.05 (0.56–1.98)
0.864
AC+CC
90
81
Dominant model
AC+AA
83
74
0.98 (0.55–1.77)
0.972
CC
34
30
Codominant model
AC
56
51
0.95 (0.56–1.61)
0.861
CC+AA
61
53
Allele
C
124 (52.99%)
111 (53.37%)
1.01 (0.69–1.47)
0.937
A
110 (47.01%)
97 (46.63%)
OR: odds ratio, CI: confidence interval, and n: number of samples.
