miR-455 Inhibits the Viability and Invasion by Targeting RAB18 in Hepatocellular Carcinoma

Figure 5

RAB18 restores partial functions of miR-455 on cell viability and invasion. (a) RAB18 was overexpressed in HCC tissues versus nontumor tissues vs NT, ^∗P < 0.05. (b) The expression of RAB18 was higher in HCC-LM3, Huh7, and Bel-7402 than in L-O2 cells vs L-O2, ^∗P < 0.05; ^∗∗P < 0.01. (c) RT-qPCR revealed the transfection efficiency of overexpressing RAB18 in miR-455 mimic-tranfected cells vs miR-455 mimic, ^∗P < 0.05. (d) RAB18 reversed partial functions of miR-455 on cell viability vs miR-455 mimic, ^∗P < 0.05. (e) Overexpressing RAB18 improved cell invasive ability in miR-455 mimic-transfected cells vs miR-455 mimic, ^∗P < 0.05.

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