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Genes | Full name | Category | Gene card ID | Function |
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ARL8B | ADP Ribosylation Factor Like GTPase 8B | Protein Coding | GC03P005122 | Plays a role in lysosome motility |
USP10 | Ubiquitin Specific Peptidase 10 | Protein Coding | GC16P084734 | A key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes |
AMBRA1 | Autophagy and Beclin 1 Regulator 1 | Protein Coding | GC11M061101 | Regulates autophagy and development of the nervous system |
LGALS8 | Galectin 8 | Protein Coding | GC01P236518 | A sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy |
AKT1S1 | AKT1 Substrate 1 | Protein Coding | GC19M049869 | Regulates cell growth and survival in response to nutrient and hormonal signals |
BNIP3 | BCL2 Interacting Protein 3 | Protein Coding | GC10M131966 | Participates in mitochondrial protein catabolic process leading to the degradation of damaged proteins inside mitochondria |
VPS18 | Vacuolar Protein Sorting Protein 18 | Protein Coding | GC15P040894 | Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. |
SAFB2 | Scaffold Attachment Factor B2 | Protein Coding | GC19M005587 | Functions as an estrogen receptor corepressor and can also inhibit cell proliferation |
PTPRS | Protein Tyrosine Phosphatase Receptor Type S | Protein Coding | GC19M005157 | Required for normal brain development |
CDK5 | Cyclin Dependent Kinase 5 | Protein Coding | GC07M151053 | Essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death |
MAPKAP1 | MAPK Associated Protein 1 | Protein Coding | GC09M125437 | Regulates cell growth and survival |
TBC1D14 | TBC1 Domain Family Member 14 | Protein Coding | GC04P006910 | Plays a role in the regulation of starvation-induced autophagosome formation |
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