Research Article

Combination Intensity-Modulated Radiotherapy and Sorafenib Improves Outcomes in Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis

Table 2

Overall response, AFP response, and failure pattern after treatment.

IMRT + sorafenib (n = 36)IMRT (n = 46) value
n (%)n (%)

Overall response0.120
 CR0 (0.0)1 (2.2)
 PR22 (61.1)20 (43.5)
 SD10 (27.8)13 (28.3)
 PD4 (11.1)12 (26.0)
AFP response0.003
 ≥20%22 (61.1)13 (28.3)
 <20%14 (38.9)33 (71.7)
Failure pattern
 In-field recurrence7 (19.4)16 (34.8)0.125
 Out-field recurrence14 (38.9)12 (26.1)0.216
 Distant metastasis6 (16.7)8 (17.4)0.931

CR, complete response; PR, partial response; SD, stable disease; PD, progression disease.