Elevated P-Element-Induced Wimpy-Testis-Like Protein 1 Expression Predicts Unfavorable Prognosis for Patients with Various Cancers

Table 2

Subgroup meta-analysis of pooled HRs for overall survival.

Variables	Studies (n)	Number of patients	HR (95% CIs)	value	I2 (%)	Ph
(1) Overall survival	10	1698	1.80 (1.52–2.14)	<0.00001	10	0.35
(2) Region
China	6	916	2.01 (1.63–2.48)	<0.00001	0	0.82
Europe	4	782	1.46 (1.09–1.97)	0.01	39	0.18
(3) Sample size
≤150	5	468	2.12 (1.58–2.83)	<0.00001	22	0.28
>150	5	1230	1.66 (1.34–2.05)	<0.00001	0	0.53
(4) Extract method
Survival curve	2	211	1.85 (1.21–2.82)	0.004	74	0.05
Multivariate analysis	8	1487	1.80 (1.49–2.17)	<0.00001	10	0.35
(5) Cancer type
Gastrointestinal cancer	5	850	1.97 (1.55–2.49)	<0.00001	0	0.72
Other	5	848	1.97 (1.55–2.49)	<0.0001	42	0.14

HR: hazard ratios; CIs: confidence intervals.