| | Age—median (range, IQR) | 28 (15–74, 25–37) | | Gender–% (n) | Female: 59.1% (55/93) | | Prior smokinga | 25.3% (22/87) | | BMI (kg/m2)—median (range, IQR) | 23.2 (15.4–40.1, 20.8–27.2) | | Obesity, % (n) | 7.6 (7) | | Hemoglobin (g/dL)—median (range, IQR) | 12.1 (3.8–15.8, 11.3–13.3) | | Neutrophils (×109/L)—median (range, IQR) | 6.6 (1.8–16.6, 4.5–9.6) | | Lymphocytes (×109/L)—median (range, IQR) | 1.1 (0.1–9.5, 0.6–1.6) | | Monocytes (×109/L)—median (range, IQR) | 0.8 (0–2.8, 0.6–1.2) | | LMR (lymphocyte-to-monocyte ratio)—median (range, IQR) | 1.3 (0.15–8.6, 0.9–2) | | Platelets (×109/L)–—median (range, IQR) | 361 (149–837, 290–440) | | Albumin (g/dl)–—median (range, IQR) | 3.9 (1.5–5.1, 3.5–4.3) | | Abnormal lactate dehydrogenase (>ULN) | 86.9% | | Abnormal lactate dehydrogenase (>2x ULN) | 52.2% (48/92)b | | Staging method | PET, 84.7% | | CTs plus BM biopsy, 12.1% | | CTs without BM biopsy, 3.2% | | Ann Arbor staging§ | I (13, 14.3%) | | II (39, 42.8%) | | III (10, 11%) | | IV (29, 31.9%) | | Contiguous extranodal disease | Pleura (61.5%) | | Pericardium (44.6%) | | Lungs (32.3%) | | Bones (30.8%) | | Heart (6.2%) | | Noncontiguous extranodal disease | Kidneys (48%) | | Pancreas (32%) | | Lungs (28%) | | Adrenal (24%) | | Bones (16%) | | Bulky disease, % (n) | 92.1% (82/89) | | B-symptoms % (n) | 75.8% (69/91)c | | ECOG, % (n) | 0–2 : 91.2% (83/91)c | | R-IPI | | | Very good | 9/87 (10.3%) | | Good | 46/87 (52.9%) | | Poor | 32/87 (36.8%) |
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IQR, interquartile range; BMI, body mass index; ULN, upper limit of normal; ECOG, Eastern Cooperative Study Group; IPI, International Prognostic Index; aaIPI, Age-adjusted International Prognostic Index; a missing data in 6 patients; b missing data for one patient; cmissing data for two patients.
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