Research Article

Less Intensive Regimens May Still Be Suitable for the Initial Treatment of Primary Mediastinal B-Cell Lymphoma in Resource-Limited Settings

Table 2

Comparison among baseline characteristics of the three treatment groups.

DA-R-EPOCH (n = 39)R-CHOP (n = 33)R-CHOEP (n = 18)-value

Sex (female, %)5957.661.10.970
Age (mean)30.33630.10.073
LDH (mean)3.2922.440.035
LDH (>2ULN, %)64.140.644.40.113
Albumin (mean)3.74.14.030.023
B-symptoms (%)74.480.672.20.753
LMR (mean)1.482.121.440.110
LMR (<1.3, %)53.836.452.90.291
Thrombosis (%)38.532.341.20.794
Advanced stage (%)53.825.844.40.06
Bulky disease (%)92.390.393.80.912
Cytoreductive COP (%)48.763.623.50.027
R-IPI0.21
 Very good6/39 (7.7%)4/29 (13.8%)2/20 (10%)
 Good22/39 (56.4%)12/29 (41.4%)12/20 (60%)
 Poor14/39 (35.9%)13/29 (44.8%)6/20 (30%)
aaIPI0.22
 Low3 (7.7%)4 (13.8%)2/20 (10%)
 Low-intermediate11 (28.2%)8 (27.6%)9 (45%)
 High-intermediate19 (48.7%)11 (37.9%)7 (35%)
 High6 (25.4%)6 (20.6%)2 (10%)