Research Article
Identification of Biomarkers Associated with Cancerous Change in Oral Leukoplakia Based on Integrated Transcriptome Analysis
Table 4
Comparison of the previous diagnosis model and the diagnosis model of this study.
| Year | Author | Molecular mark | AUC | CI |
| 2021 | Verification in external dataset | DCT, KRT3, KRT76, and FAM3B | 0.745 | 0.638–0.851 | 2006 | Norhany et al. [17] | PAX5 | 0.521 | 0.395–0.647 | 2011 | Cao et al. [18] | EZH2 | 0.572 | 0.443–0.701 | 2011 | Quitllet et al. [19] | CKS1B | 0.618 | 0.497–0.740 | 2017 | Sakata et al. [20] | SMAD4 | 0.541 | 0.412–0.670 | 2018 | Saintigny et al. [21] | MET | 0.709 | 0.599–0.820 | 2019 | Herrera Costa et al. [7] | ALDH1A1 and ALDH1A2 | 0.600 | 0.475–0.725 | 2021 | Cai et al. [6] | SPP1 | 0.706 | 0.593–0.820 |
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AUC : area under the curve; CI : confidence interval.
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