Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib

<div>The upregulation of UNC5B in ovarian cancer is associated with poor prognosis of ovarian cancer. (a) Big data analysis of UNC5B expression in normal and ovarian cancer patients. (b) Survival analysis of ovarian cancer patients with different UNC5B expression levels. (c) UNC5B immunohistochemical test results in normal ovarian tissue and ovarian cancer tissue. The experimental results were obtained from the Human Protein Atlas website (<a href="http://www.proteinatlas.org/">http://www.proteinatlas.org/</a>). (d) The statistical results of immunohistochemical detection of UNC5B in normal ovarian tissue and ovarian cancer tissue. (e) RT-qPCR analysis of UNC5B expression in tissues. 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Journal of Oncology

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Figure 1

Figure 1: Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib 

Figure 1 | Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib 