Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib

<div>OA inhibits UNC5B and the malignant progression of ovarian cancer cells. (a) After different treatments, SKOV3 cell proliferation detected. (b) Transwell detection of SKOV3 cells after different treatments. (c) After different treatments, the clone formation ability of SKOV3 cells was tested. (d) qRT-PCR detecting the changes in UNC5B expression in SKOV3 cells after different treatments. (e) qRT-PCR detecting the change of E-cadherin expression in SKOV3 cells after different treatments. (f) qRT-PCR detecting the changes of vimentin expression in SKOV3 cells after different treatments. (g) Detection of Twist1 expression in SKOV3 cells after different treatments by qRT-PCR. 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Journal of Oncology

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Figure 4

Figure 4: Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib 

Figure 4 | Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib 