Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study

Table 1

Baseline characteristics of the sample population (whites and blacks combined) according to TCF7L2 genotype, the ARIC study cohort.

Characteristic	CC	CT	TT
	$n=\mathrm{6,736}$	$n=\mathrm{5,583}$	$n=\mathrm{1,177}$
Age (years)	54.0 (5.7)	53.9 (5.8)	54.1 (5.8)
BMI (kg/m^2)	27.8 (5.4)	27.6 (5.3)	27.5 (4.9)
HDL-cholesterol (mmol/L)	1.4 (0.4)	1.4 (0.4)	1.3 (0.4)
Fasting glucose (mmol/L)	6.0 (2.2)	6.1 (2.2)	6.2 (2.3)
Gender (% Male)	42.8	43.9	44.8
Race (% Black)	26.9	27.2	25.7
Diabetes (%)	9.6	12.5	14.5
Hypertension (%)	33.7	34.6	31.1
Ever smoker (%)	56.5	57.4	58.6

*differences across genotype strata were significant at $\alpha =0.05$ only for BMI $(P=.03),$ diabetes $(P<.01),$ and fasting glucose $(P<.01).$