Mendelian Randomisation Study of Childhood BMI and Early Menarche
Table 1
Characteristics of EPIC-Norfolk women included in the current study.
Included women
Excluded women
Mean
SD
Mean
SD
*
value
Age at baseline visit (years)
8,156
58.2
9.2
2,801
59.8
9.3
<.001
Height at baseline visit (cm)
8,156
161.1
6.2
2,503
160.5
6.2
<.001
Weight at baseline visit (kg)
8,150
67.6
11.5
2,510
68.3
12.1
.004
Weight at age 20 (kg)
8,156
56.8
8.0
804
56.5
7.8
.2
BMI at age 20 (kg/m2)
8,156
21.9
2.8
559
21.7
2.6
.2
Age at menarche (years)
8,156
13.0
1.6
2,241
13.0
1.6
.04
Inclusion criteria were complete genotype data on at least 9 SNPs, available height measurement and recalled information on age at menarche between 8 to 18 years, and body weight at age 20 years.
*
values for unpaired -test.
