Journal of Obesity / 2011 / Article / Tab 2

Research Article

Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy

Table 2

UCP1 sequence variations and their frequencies in obese and control subjects.

PolymorphismsObese patientsControl subjects
Positionrs#wtHEHOwtHEHO

g.−637T>C1991010000
g.−451C>Trs362074108216286140
g.−412A>Crs38117875736749438
g.−372A>Crs180066097309730
g.−206C>A1991010000
g.−56C>Trs3749539919090100
g.−17C>G194609460
g.12A>Crs10011540919090100
g.21G>Ars18006618613179210
g.940G>A (p.A64T)rs4553993392809190
g.IVS2+138C>Trs76887438015570273
g.IVS2+174T>A1991010000
g.IVS2+201T>Grs20714167921077221
g.IVS4−208T>G2rs149480845441169238
g.6537A>T (p.M229L)rs22705658911087130

1New variants; 2More frequent polymorphism in obese patients ( ) than in controls. wt: wild-type homozygous subjects; HE: heterozygous and HO: homozygous subjects at level of the detected variant.

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