Review Article

Genetic Variance in Uncoupling Protein 2 in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional −866G>A Promoter Variant (rs659366)

Figure 2

Diagram of the UCP2-UCP3 genomic region with indications of common genetic variation. Genomic organization of the UCP2-UCP3 region on chromosome 11. ATG: start codon, TGA: stop codon. Bent arrows indicate reported transcription start sites (from [34]). UCP3 protein exists in a short and a long form due to alternative polyadenylation sites, indicated by TGAS and TGAL [35].
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