Hepatoportal Leptin Sensors and Their Reflex Effects on Autonomic Outflow in the Rat

Table 2

Reflex responses of sympathetic and vagal efferents following IV injection of leptin (l ng, 0.1 mL).

Impulses/5 seconds ± SE
	Before injection		30 minutes	60 minutes	90 minutes
Sympathetic efferents
Adrenal efferents (𝑛=5)	70.7±2.7		83.6±5.4^∗	92.0±6.8^∗	95.5±6.8^∗
WAT efferents (𝑛=5)	69.3±1.8		84.8±10.8	95.3±9.4^∗	102.3±9.6^∗
BAT efferents (𝑛=5)	65.0±3.7		100.2±16.0^∗	106.3±20.6^∗	110.7±26.2^∗
Splenic efferents (𝑛=5)	71.4±4.9		79.3±5.0	110.0±19.6	132.8±35.2^∗
Vagal efferents
Vagal celiac efferents (𝑛=5)	63.5±2.4		50.6±4.7^∗∗	53.0±3.2^∗∗	56.2±3.9

(*Significant increase, **significant decrease, 𝑃<.05).