Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice
Figure 5
Sensory nerve conduction velocity, thermal nociception, and intraepidermal nerve fiber profiles for C57Bl/6J mice fed a normal or high-fat-containing diet with or without ilepatril, candoxatril, or enalapril for 12 weeks (prevention protocol). Control (open bar), high fat (right hatch bar), high fat + ilepatril (left hatch bar), high fat + candoxatril (cross hatch bar), and high fat + enalapril (closed bar). Data are the mean ± SEM. The number of mice in each group was the same as shown in Table 1. a, versus control; b, versus high-fat-fed mice.
