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Journal of Obesity
Volume 2012, Article ID 369097, 6 pages
Review Article

Weight Loss Is Still an Essential Intervention in Obesity and its Complications: A Review

China-Japan Friendship Hospital, Beijing 100029, China

Received 27 February 2012; Accepted 1 May 2012

Academic Editor: Nomelí P. Núñez

Copyright © 2012 Jianzhong Xiao and Wenying Yang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The prevalence of obesity is more than 20% in many developed countries and it increases in developing countries. Obesity is associated with metabolic disorders, cardiovascular diseases, pulmonary diseases, digestive diseases, and cancers. Although other specific treatments for these complications exist, weight loss is still an essential intervention in obesity and its complications. Therapeutic life change, behavior modification, pharmacotherapy, and surgery are major approaches to weight loss. In addition, medicine used in diabetes such as Glucagon-like peptide-1 analogues may be a new type of medicine for obesity, at least for those obese patients with diabetes.