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Journal of Obesity
Volume 2012, Article ID 516350, 7 pages
Clinical Study

Independent Benefits of Meeting the 2008 Physical Activity Guidelines to Insulin Resistance in Obese Latino Children

1Department of Pediatrics, Children’s National Medical Center, The George Washington University Medical Center, Washington, DC 20010, USA
2Department of Pediatrics, The George Washington University Medical Center, Washington, DC 20037, USA
3Department of Exercise Science, School of Public Health and Health Services, The George Washington University Medical Center, 817 23rd Street, NW, Washington, DC 20052, USA

Received 15 November 2011; Revised 12 December 2011; Accepted 21 December 2011

Academic Editor: David John Stensel

Copyright © 2012 Nazrat Mirza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We examined the independent association between moderate-to-vigorous physical activity (MVPA) and insulin resistance (IR) among obese Latino children (N=113; 7–15 years) who were enrolled in a community-based obesity intervention. Baseline information on physical activity was gathered by self-report. Clinical assessments of body composition, resting energy expenditure (REE), as well as glucose and insulin responses to an oral glucose tolerance test (OGTT) were performed after an overnight fast. Insulin resistance was defined as a 2 h insulin concentration >57 μU·mL-1. We observed that those obese children who met the 2008 Guidelines for MVPA (≥60 min/day) experienced a significantly lower odds of IR compared with those not meeting the Guidelines (OR=0.29; 95% CI: (0.10–0.92)) and these findings were independent of age, sex, pubertal stage, acculturation, fasting insulin, and 2 h glucose concentrations. Efforts to promote 60 min or more of daily MVPA among children from ethnic minority and high-risk communities should assume primary public health importance.