Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats

Table 3

Tibial material properties.

	Lean	Obese	𝑛
Modulus of elasticity (GPa)	1.60 ± 0.24	1.59 ± 0.25	9423
Stress at proportional limit (MPa)	27.90 ± 2.81^*	33.12 ± 6.14
Strain at proportional limit (%)	1.97 ± 0.36	2.29 ± 0.09	8
Stress at maximal load (MPa)	39.53 ± 4.45	42.96 ± 6.16	38
Strain at maximal load (%)	4.60 ± 0.98	4.58 ± 0.76	29705
Mineral ash fraction (%)	71.94 ± 0.28	72.53 ± 0.43	9

Values are means ± SD. ^*denotes statistically significant (𝑃≤0.05). 𝑛 denotes the sample size per group needed for the recorded differences to become statistically significant based on a power of 0.8.