Research Article

Influence of Weight Loss, Body Composition, and Lifestyle Behaviors on Plasma Adipokines: A Randomized Weight Loss Trial in Older Men and Women with Symptomatic Knee Osteoarthritis

Table 5

Spearman correlations at baseline and 6 months for women between adipokines and body fat %, trunk fat, step counts, dietary intake, and peak METS from GXT (baseline only). Data are presented as rho correlation coefficient ( value).

LeptinSoluble leptin receptorAdiponectinFree leptin indexLeptin : adiponectin

Body fat (%)
 Baseline0.440 (0.022)*−0.090 (0.656)0.015 (0.940)0.369 (0.058) 0.333 (0.089)
 6 months0.757 ( )*0.347 (0.076) −0.067 (0.739)0.631 ( )*0.562 (0.002)*
Trunk fat
 Baseline0.099 (0.624)0.226 (0.256)0.136 (0.498)0.046 (0.821)0.018 (0.928)
 6 months0.471 (0.013)*0.368 (0.059) −0.167 (0.406)0.335 (0.087) 0.454 (0.017)*
METS
 Baseline−0.276 (0.172)−0.091 (0.657)−0.026 (0.900)−0.198 (0.333)−0.193 (0.344)
 6 months#####
Step counts
 Baseline−0.054 (0.792)0.157 (0.444)0.172 (0.401)−0.147 (0.475)−0.085 (0.679)
 6 months−0.464 (0.034)*0.022 (0.924)0.261 (0.253)−0.408 (0.067) −0.349 (0.121)
Energy intake
 Baseline−0.050 (0.807)0.411 (0.037)*0.213 (0.296)−0.156 (0.446)−0.161 (0.432)
 6 months−0.121 (0.555)0.320 (0.111)−0.065 (0.751)−0.206 (0.312)0.006 (0.978)
Fat intake (%)
 Baseline−0.246 (0.225)0.198 (0.332)−0.062 (0.764)−0.209 (0.306)−0.226 (0.267)
 6 months0.032 (0.875)0.449 (0.021)*0.105 (0.610)−0.115 (0.575)−0.033 (0.872)
Carbohydrate intake (%)
 Baseline0.498 (0.010)*−0.221 (0.278)−0.048 (0.815)0.413 (0.036)*0.428 (0.029)*
 6 months−0.087 (0.672)−0.160 (0.434)−0.136 (0.506)−0.030 (0.883)0.069 (0.739)
Protein intake (%)
 Baseline−0.269 (0.184)−0.342 (0.088) 0.212 (0.298)−0.056 (0.787)−0.265 (0.191)
 6 months0.148 (0.470)−0.393 (0.047)*0.120 (0.559)0.246 (0.226)−0.035 (0.864)

Indicates statistical significance at ; indicates value ≥ 0.050 and < 0.100.
# Indicates that comparisons were only from baseline measures of METS.