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Journal of Obesity
Volume 2012 (2012), Article ID 969124, 9 pages
Research Article

The Impact of Abdominal Obesity Status on Cardiovascular Response to the Mediterranean Diet

1Institute of Nutraceuticals and Functional Foods, Laval University, 2440 Hochelaga Boulevard, QC, Canada G1V 0A6
2Department of Food Science and Nutrition, Pavillon Paul-Comtois, Laval University, 2425 Rue de l'Agriculture, QC, Canada G1V 0A6
3Department of Obstetrics and Gynaecology, Pavillon Ferdinand-Vandry, Laval University, 1050 Medicine Avenue, QC, Canada G1V 0A6

Received 4 July 2012; Revised 10 September 2012; Accepted 18 September 2012

Academic Editor: Robert Ross

Copyright © 2012 Alexandra Bédard et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We investigated the impact of abdominal obesity status on the cardiovascular response to a fully controlled 4-week isoenergetic Mediterranean diet (MedDiet). Thirty-eight abdominally obese individuals (waist circumference >102 cm in men and >88 cm in women) and thirty-one nonabdominally obese individuals were recruited and studied before and after the MedDiet. All analyses were adjusted for the slight decrease in body weight, which occurred during the MedDiet (mean:  kg). A group by time interaction was noted for waist circumference ( ), abdominally obese subjects showing a significant decrease and nonabdominally obese subjects a nonsignificant increase (resp., −1.1 and +0.3%). The MedDiet resulted in decreases in total cholesterol, LDL-C, HDL-C, apolipoprotein B, A-1, and A-2, total cholesterol/HDL-C ratio, LDL-C/HDL-C ratio, and systolic and diastolic blood pressure (time effect: ). For all variables related to glucose/insulin homeostasis, no change was observed except for a decrease in 2 h glucose concentrations (time effect: ). No group by time interaction was observed in any of the metabolic variables studied. Results from our study suggest that the adoption of the MedDiet leads to beneficial metabolic effects, irrespective of the abdominal obesity status.