Research Article

The Epidemiological Boehringer Ingelheim Employee Study—Part I: Impact of Overweight and Obesity on Cardiometabolic Risk

Table 4

BMI-dependent risk determination.

ParameterOR [CI]1  
for continuous BMI
OR [CI]2   
for BMI 25.0–29.9 kg/m2  
BMI ≥ 30.0 kg/m2
Sex- and age-adjusted OR [CI]2  
 for BMI 25.0–29.9 kg/m2  
BMI ≥ 30.0 kg/m2

Hypertension1.22 [1.19–1.25]3.3 [2.7–4.0]  
8.0 [6.2–10.3]
2.5 [2.1–3.1]  
6.3 [4.8–8.2]
Hypertriglyceridemia1.18 [1.15–1.20]4.0 [3.2–5.1]  
7.4 [5.7–9.7]
3.2 [2.5–4.1]  
6.3 [4.8–8.3]
Hypercholesterolemia1.05 [1.03–1.07]1.6 [1.3–1.9]  
1.5 [1.2–1.9]
1.4 [1.2–1.6]  
1.3 [1.04–1.6]
Metabolic syndrome1.34 [1.30–1.37]15.1 [10.5–21.6]  
42.3 [28.8–62.2]
10.9 [7.5–15.7]  
35.9 [24.1–53.4]
Hyperinsulinemia1.31 [1.28–1.35]3.9 [2.6–5.9]  
22.8 [15.3–34.1]
3.3 [2.2–5.0]  
19.4 [12.9–29.1]
Insulin resistance1.35 [1.31–1.38]4.8 [3.6–6.4]  
24.7 [18.0–33.9]
4.1 [3.0–5.5]  
21.7 [15.8–29.8]
Type 2 diabetes mellitus1.18 [1.14–1.21]3.3 [1.8–6.0]  
9.3 [5.2–16.7]
3.0 [1.7–5.6]  
8.2 [4.5–14.9]
Increased IMT1.15 [1.09–1.20]2.9 [1.4–6.3]  
7.3 [3.4–15.7]
1.6 [0.7–3.5]  
3.8 [1.7–8.4]
Arteriosclerosis1.07 [1.05–1.10]1.9 [1.5–2.4]  
2.4 [1.8–3.2]
1.4 [1.03–1.8]  
1.6 [1.1–2.2]
Cardiovascular disease1.03 [0.99–1.06]1.2 [0.9–1.7]  
1.4 [0.9–2.2]
1.2 [0.8–1.7]  
1.3 [0.9–2.0]

For definitions of parameters, see Table 3 legend. 1Odds ratios (ORs) and confidence intervals (CIs) were estimated corresponding to 1.0 kg/m² change for BMI. 2ORs were estimated versus the lowest BMI class (<25 kg/m²). ORs significantly different from 1.0 were bold written.