Altered Hepatic Lipid Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice
Figure 1
Increased body weight and reduced insulin sensitivity are characteristics of leptin deficient Ob/Ob mice. Body weight (a), fasting blood glucose (b), fasting plasma insulin (c), and homeostasis model assessment (HOMA) (d) were elevated in 14-week-old male Ob/Ob mice as compared to age-matched male wild-type (WT) mice. Values are means SE (); *.