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Journal of Obesity
Volume 2013, Article ID 325464, 12 pages
Clinical Study

Changes in Body Composition, Cardiovascular Disease Risk Factors, and Eating Behavior after an Intensive Lifestyle Intervention with High Volume of Physical Activity in Severely Obese Subjects: A Prospective Clinical Controlled Trial

1Department of Sports Medicine, The Norwegian School of Sport Sciences, P.O. Box 4014 Ullevaal Stadion, 0806 Oslo, Norway
2Department of Endocrinology, Obesity and Preventive Medicine, Oslo University Hospital, P.O. Box 4956 Nydalen, 0424 Oslo, Norway
3NIMI, P.O. Box 3843 Ullevaal Stadion, 0805 Oslo, Norway

Received 15 February 2013; Revised 25 March 2013; Accepted 28 March 2013

Academic Editor: Daniel Weghuber

Copyright © 2013 Kjersti Karoline Danielsen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We examined the effects of a 10–14-weeks inpatient lifestyle modification program, including minimum 90 min of physical activity (PA) five days/week, on body composition, CVD risk factors, and eating behavior in 139 obese subjects (BMI  kg/m2). Completion rate was 71% in the intensive lifestyle intervention (ILI) group and 85% among waiting list controls. Compared to controls body weight ( (95% CI:  , ) kg, ), fat mass ( (95% CI:  , ) kg, ), fat free mass ( (95% CI:  , ) kg, ) and visceral fat ( (95% CI:  , ) cm2, ) were reduced in the ILI-group after 10–14 weeks. Within the ILI-group weight loss was (95% CI:  , ) kg, and (95% CI:  , ) kg, , after six and 12 months, respectively. Systolic BP, glucose, triglycerides, and LDL-C were reduced, and HDL-C was increased (all ) after 10–14 weeks within the ILI group. The reduction in glucose and increase in HDL-C were sustained after 12 months (all ). After one year, weight loss was related to increased cognitive restraint and decreased uncontrolled eating (all ). Thus, ILI including high volume of PA resulted in weight loss with almost maintenance of fat-free mass, favorable changes in CVD risk factors, and eating behavior in subjects with severe obesity.