Alterations in Phosphorylated CREB Expression in Different Brain Regions following Short- and Long-Term Morphine Exposure: Relationship to Food Intake

Figure 2

Body weight change (% of initial body weight) (a) and food intake (g/day) (b) following different morphine treatments. See Table 1 for details on the morphine treatment paradigm. 𝑁=3-4 per treatment. *𝑃<0.05, versus saline injection, ^##𝑃<0.0001 versus 24 h placebo pellet, ^∧𝑃<0.05 versus 7 d placebo pellet, ^∧∧𝑃<0.0001 versus 7 d placebo pellet.

(a)

(b)