Journal of Obesity / 2015 / Article / Tab 2

Research Article

Obesity and Metabolic Phenotypes (Metabolically Healthy and Unhealthy Variants) Are Significantly Associated with Prevalence of Elevated C-Reactive Protein and Hepatic Steatosis in a Large Healthy Brazilian Population

Table 2

Prevalence and odds ratios for vascular inflammation and hepatic steatosis across weight and metabolic risk factor based phenotypes.

Prevalence of Elevated hsCRP
OverallMales onlyFemales only
(%)UORAOR (%)UORAOR (%)UORAOR

Metabolically healthy normal weight (referent)223 (12%)1196 (9%)11127 (16%)11
Metabolically unhealthy normal weight44 (17%)1.51
(1.06–2.14)
2.00
(1.31–3.06)
35 (17%)2.10
(1.38–3.20)
1.96
(1.23–3.11)
9 (18%)1.10
(0.52–2.32)*
1.24
(0.58–2.63)*
Metabolically healthy obese452 (22%)2.11
(1.78–2.52)
2.45
(1.92–3.12)
335 (19%)2.51
(1.97–3.19)
2.52
(1.94–3.27)
117 (40%)3.32
(2.45–4.48)
3.59
(2.63–4.90)
Metabolically unhealthy obese343 (25%)2.46
(2.04–2.96)
2.89
(2.25–3.73)
283 (22%)3.02
(2.36–3.86)
2.93
(2.24–3.84)
60 (56%)6.40
(4.18–9.81)
7.84
(4.95–12.41)

Prevalence of Hepatic Steatosis
OverallMales OnlyFemales Only
(%)UORAOR (%)UORAOR (%)UORAOR

Metabolically healthy normal weight (referent)152 (8%)11137 (13%)1115 (2%)11
Metabolically unhealthy normal weight70 (27%)4.12
(2.99–5.68)
3.03
(2.12–4.32)
62 (30%)2.94
(2.08–4.17)
2.60
(1.82–3.69)
8 (16%)9.30
(3.7–23.15)
6.67
(2.59–17.18)
Metabolically healthy obese805 (40%)7.49
(6.20–9.05)
5.80
(4.72–7.13)
756 (71%)5.50
(4.49–6.74)
5.30
(4.32–6.50)
49 (17%)10.13
(5.58–18.40)
8.57
(4.67–15.73)
Metabolically unhealthy obese952 (70%)25.76
(21.04–31.54)
17.64
(14.14–22.01)
894 (71%)17.03
(13.71–21.15)
15.18
(12.19–19.49)
58 (56%)62.89
(33.08–119.56)
44.41
(22.81–86.49)

UOR: unadjusted odds ratio (95% confidence interval).
AOR: adjusted odds ratio (95% confidence interval), adjusted for age, gender, LDL, smoking history, and physical activity.
(%) represents number and percentage of subjects with outcome of interest (steatosis or elevated hsCRP) among a specific phenotype (MHNW, MUNW, MHO or MUHO).
value > 0.05. All other data has associated unless otherwise noted.