Bile Acids, FXR, and Metabolic Effects of Bariatric Surgery

Table 1

Location of FXR and MAFA consensus binding sequences within 1000 bp of complement alternative activation pathway genes. C3aR and C5aR genes lack either motif.

Gene	Motif	Position	Location
C3	FXR	−154	Upstream
C5	FXR	−454	Upstream
Factor B	FXR	−172	Upstream
Adipsin	FXR	−417	Upstream
CpB	FXR	537	Downstream
C5L2	FXR	−81	Upstream
C5L2	MAFA	−102	Upstream
C3aR	None	—	—
C5aR	None	—	—