Research Article

FTO Gene Associates and Interacts with Obesity Risk, Physical Activity, Energy Intake, and Time Spent Sitting: Pilot Study in a Nigerian Population

Table 1

Characteristics of the study population.

CharacteristicsOverall
()
Female
()
Male
()

Age (years)22.64 (3.61)23.05 (3.69)22.22 (3.50)0.105
Anthropometric
Body weight (kg)66.98 (9.54)62.54 (7.80)71.56 (9.03)<0.001
BMI (kg/m2)25.96 (3.06)25.52 (3.15)26.41 (2.91)0.044
 Normal (n; %)98; 48.8045; 22.4053; 26.400.182
 Overweight/obesity (n; %)103; 51.2057; 28.4046; 22.900.322
NC (cm)31.24 (4.00)30.78 (5.06)31.25 (4.34)0.121
WC (cm)81.67 (8.02)80.91 (7.50)82.47 (8.48)0.169
 Central obesity (n; %)65; 32.3056; 27.909; 4.50<0.001
WHR0.881 (0.081)0.862 (0.070)0.899 (0.088)0.001
 Central obesity (n; %)107; 53.2057; 28.4050; 24.900.445
WHtR0.507 (0.055)0.514 (0.053)0.499 (0.056)0.038
 Visceral obesity (n; %)110; 54.7062; 30.8048; 23.900.08
R2D : 4D0.9711 (0.027)0.9819 (0.027)0.9600 (0.022)<0.001
L2D : 4D0.9684 (0.024)0.9791 (0.023)0.9573 (0.021)<0.001
Energy intake (kcal/day)1848.76 (431.17)1763.73 (397.96)1936.36 (448.23)0.004
Time spent siting (minutes/week)411.19 (183.12)400.98 (173.53)421.72 (192.82)0.424
Physical activity (PA)
 Total PA (MET-minutes/week)678 (4177–40)643.5 (3405–40)1335 (4177–188.5)<0.001
 Light PA (MET-minutes/week)396 (1782–0)280.5 (1782–0)495 (1782–33)<0.001
 Moderate PA (MET-minutes/week)180 (1800–0)120 (1800–0)320 (1680–0)<0.001
 Vigorous PA (MET-minutes/week)80 (1800–0)0 (1800–0)80 (1800–0)0.072

Data are presented as means (standard deviation (SD) values shown in parenthesis) except stated otherwise. The difference was evaluated using Student’s T-test and Chi-square test for continuous and categorical variables, respectively; BMI: body mass index, NC: neck circumference, WC: waist circumference, WHR: waist to hip ratio, WHtR: waist to height ratio, R2D : 4D: ratio of right hand second to fourth digit, and L2D : 4D: ratio of left hand second to the fourth digit; n = number of samples; % = percentage; normal BMI < 25 kg/m2 while overweight/obesity BMI ≥ 25 kg/m2; central obesity was defined as WC > 80 cm for female and > 94 cm for male; central obesity was defined as for female and >0.90 for male; visceral obesity was defined as WHtR > 0.5; total energy intake per day from carbohydrate sources; data expressed by median (range); Mann–Whitney U test.