Predictors of Insulin Resistance in Children versus Adolescents with Obesity
Table 3
Laboratory results of obese children and adolescents, stratified by IR.
Children n = 306
Adolescents n = 471
IR n = 51
No IR n = 255
value
IR n = 233
No IR n = 238
value
FPG (mmol/L)
5.1 (0.5)
4.9 (0.4)
<0.001
5.2 (0.5)
5.0 (0.4)
<0.001
FPI (mU/L)
19.5 (11.0–50.2)
5.4 (1.0–16.0)
<0.001
24.0 (13.9–69.0)
9.0 (1.1–15.7)
<0.001
HOMA-IR
4.38 (3.4–13.4)
1.16 (0.2–3.3)
<0.001
4.85 (3.4–19.9)
1.99 (0.3–3.3)
<0.001
TC (mmol/l)
4.30 (0.73)
4.32 (0.74)
0.716
4.3 (0.85)
4.3 (0.77)
0.949
HDL (mmol/l)
1.2 (0.34)
1.3 (0.30)
0.039
1.15 (0.26)
1.27 (0.29)
<0.001
LDL (mmol/l)
2.6 (0.71)
2.49 (0.62)
0.291
2.6 (0.75)
2.5 (0.69)
0.525
TG (mmol/l)
1.4 (0.46)
0.9 (0.63)
<0.001
1.29 (0.66)
1.04 (0.54)
<0.001
Data presented mean (standard deviation) or median with range. FPG = fasting plasma glucose, FPI = fasting plasma insulin, HOMA-IR = homeostatic assessment for IR, IR = insulin resistance, TC = total cholesterol, TG = triglycerides. values for unpaired t-test (normally distributed data) and Mann–Whitney U test (nonparametric data). P values in bold are significant at <0.05.
