Research Article
Changes in the MicroRNA Profile Observed in the Subcutaneous Adipose Tissue of Obese Patients after Laparoscopic Adjustable Gastric Banding
Table 1
Clinical and biochemical parameters measured in three obese females (OB) before (T0) and three years after LAGB (T1).
| | | OB1 | OB2 | OB3 | | T0 | T1 | T0 | T1 | T0 | T1 |
| | BMI | 41.5 | 28.4 | 37.2 | 28.1 | 50.0 | 39.5 | | EWL (%) | | 71.4 | | 66.7 | | 36.2 | | Na+ (mmol/L) | 138.0 | 143.0 | 142.0 | 139.0 | 143.0 | 142.0 | | K+ (mmol/L) | 4.0 | 4.3 | 4.3 | 4.8 | 4.7 | 4.7 | | Ca++ (mg/dL) | 10.1 | 9.3 | 9.5 | 10.8 | 9.2 | 9.9 | | Phosphorus (mg/dL) | 3.4 | 3.1 | 3.7 | 3.4 | 2.9 | 3.6 | | Fe (µg/dL) | 90.0 | 49.0 | 145.0 | 72.0 | 47.0 | 85.0 | | Glucose (mmol/L) | 5.7 | 5.8 | 4.6 | 4.8 | 5.0 | 4.9 | | Insulin (mU/L) | 6.1 | 11.3 | 12.9 | 3.5 | 51.9 | 11.2 | | HOMA | 2.9 | 1.6 | 2.6 | 0.7 | 11.5 | 2.4 | | Cholesterol (mmol/L) | 5.0 | 4.9 | 5.0 | 4.8 | 4.1 | 4.8 | | Triglycerides (mmol/L) | 0.9 | 0.8 | 1.0 | 0.5 | 0.8 | 1.0 | | AST (U/L) | 17.0 | 15.0 | 24.0 | 13.0 | 24.0 | 26.0 | | ALT (U/L) | 20.3 | 11.0 | 24.0 | 26.0 | 23.0 | 26.0 | | ALP (U/L) | 90.0 | 74.0 | 64.0 | 58.0 | 112.0 | 110.0 | | GGT (U/L) | 16.7 | 11.0 | 20.0 | 12.0 | 15.0 | 12.0 | | LDH (U/L) | 307.0 | 375.0 | 374.0 | 102.0 | 335.0 | 336.0 | | CHE (U/L) | 10037.3 | 6497.0 | 11312.0 | 8383.7 | 8721.0 | 8855.0 | | CK (U/L) | 100.0 | 51.0 | 128.0 | 97.7 | 61.0 | 54.0 | | AMS (U/L) | 53.0 | 53.0 | 39.0 | 45.0 | 56.0 | 78.0 | | Urea (mmol/L) | 0.4 | 0.5 | 0.5 | 0.5 | 0.7 | 0.5 | | Creatinine (μmol/L) | 53.0 | 53.0 | 61.9 | 53.0 | 61.9 | 70.7 | | UA (mmol/L) | 0.3 | 0.2 | 0.3 | 0.2 | 0.3 | 0.3 | | T-bil (μmol/L) | 9.7 | 7.7 | 18.1 | 6.8 | 6.8 | 12.1 | | TP (g/dL) | 7.8 | 7.5 | 7.7 | 6.4 | 8.0 | 8.3 | | Albumin (g/dL) | 4.2 | 4.4 | 4.8 | 4.5 | 4.0 | 4.6 | | Adiponectin (µg/mL) | 9.4 | 19.5 | 7.7 | 15.7 | 9.9 | 17.1 | | Leptin (ng/mL) | 43.1 | 8.5 | 22.4 | 12.4 | 32.2 | 16.6 | | Leptin/adiponectin ratio | 4.6 | 0.4 | 2.9 | 0.8 | 3.2 | 1.0 | | Adipocyte | 31 | 55 | 35 | 48 | 31 | 46 | | Adipocyte diameter | 14 | 8 | 13 | 9 | 14 | 10 |
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from [3]. significant differences at T0 versus T1 at Wilcoxon’s test; .
ALP: alkaline phosphatase; ALT: alanine aminotransferase; AMS: amylase; AST: aspartate aminotransferase; BMI: body mass index; CHE: cholinesterase; CK: creatine kinase; EWL: excess weight loss; GGT: γ-glutamyl transferase; HOMA: homeostasis model assessment; LDH: lactate dehydrogenase; T-bil: total bilirubin; TP: total proteins; UA: uric acid.
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