Effects of Immediate or Delayed Estradiol on Behavior in Old Menopausal Macaques on Obesogenic Diet

Table 2

Time points for behavioral testing (numbers in parentheses are mean ± SD).

Time point	Description	Anxiety test performed
Baseline 0 (B0)	Approximately 2 (1.9 ± 0.7) months after introduction to the group; prior to introduction of WSD and ovariectomy	HIT; NOT; Focal observation
Baseline 1 (B1)	Approximately 3 (2.8 ± 0.6) months after B0; animals on high-fat diet; prior to ovohysterectomy	Focal observations
Year 1	Approximately 7.5 (7.5 ± 0.8) months after B1	HIT; NOT; Focal observations
Year 2	12 months after year 1	HIT; NOT; Focal observations
Year 2.5	Prior to end of study	HIT; NOT; Focal observations