A Conservative Weight Loss Intervention Relieves Bowel Symptoms in Morbidly Obese Subjects with Irritable Bowel Syndrome: A Prospective Cohort Study
Table 4
Subjects’ characteristics before and after the conservative weight loss intervention, stratified by IBS status before the intervention.
Subjects with IBS
Subjects without IBS
Before intervention
After intervention
Change during the intervention
Before intervention
After intervention
Change during the intervention
Differences in changes between subjects with and without IBS
n
n
values
n
n
n
values
n
values
IBS-severity scoring system (IBS-SSS)
218 (89)
24
132 (83)
21
<
21
75 (79)
60
63 (77)
60
56
<0.001#
Gastrointestinal Symptom Rating Scale-irritable bowel syndrome version (GSRS-IBS)
2.6 (0.7)
24
2.0 (0.7)
24
24
1.5 (0.6)
61
1.5 (0.6)
64
61
<0.001#
Pain syndrome
3.0 (1.0)
24
2.2 (1.1)
24
24
1.4 (0.7)
60
1.5 (0.8)
64
60
0.001#
Bloating syndrome
3.2 (1.3)
24
2.1 (1.0)
24
24
1.8 (1.0)
61
1.6 (0.8)
64
61
0.018#
Constipation syndrome
1.9 (1.3)
24
2.3 (1.5)
24
24
1.3 (0.6)
61
1.6 (1.1)
64
61
0.81#
Diarrhoea syndrome
2.5 (1.1)
24
1.9 (1.0)
24
24
1.5 (0.7)
61
1.4 (0.6)
64
0.46
61
0.010#
Satiety
2.2 (1.5)
24
1.4 (0.6)
24
24
1.4 (0.7)
61
1.2 (0.5)
64
61
0.053#
Number of meals/day
4.1 (0.9)
23
4.5 (1.1)
22
21
3.9 (1.0)
62
4.8 (1.1)
62
<
61
0.015#
Hopkins Symptom Checklist (HSCL-10)
1.9 (0.6)
24
1.6 (0.6)
24
24
1.5 (0.5)
64
1.4 (0.5)
64
0.006
64
0.044#
The values are given as mean (SD) or n (%). All variables from Table 3 where the change is significantly different in subjects with and without IBS are included in this table. Statistical tests with Wilcoxon signed rank test and #Mann-Whitney U test.
