Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study
Table 4
Association of clinicopathologic characteristics with BMI among premenopausal and postmenopausal breast cancer patients (N = 348).
Characteristic
Premenopausal (N = 153)
Postmenopausal (N = 195)
Normal weight (n = 43)
Overweight (n = 52)
Obese (n = 58)
P value
Normal weight (n = 21)
Overweight (n = 66)
Obese (n = 108)
value
Age (years)
<50
43 (100.0)
49 (94.2)
53 (91.4)
0.153
8 (38.1)
10 (15.2)
13 (12.0)
0.011
≥50
0 (0.0)
3 (5.8)
5 (8.6)
13 (61.9)
56 (84.8)
95 (88.0)
Histologic type
Invasive ductal
39 (90.7)
40 (76.9)
49 (84.5)
0.191
17 (81.0)
50 (75.8)
82 (75.9)
0.874
Others
4 (9.3)
12 (23.1)
9 (15.5)
4 (19.0)
16 (24.2)
26 (24.1)
Tumor stage
Early (I/II)
26 (60.5)
23 (44.2)
32 (55.2)
0.262
12 (57.1)
45 (68.2)
50 (46.3)
0.019
Advanced (III/IV)
17 (39.5)
29 (55.8)
26 (44.8)
9 (42.9)
21 (31.8)
58 (53.7)
Tumor grade
I and II
17 (39.5)
30 (57.7)
22 (37.9)
0.079
11 (52.4)
41 (62.1)
45 (41.7)
0.031
III
26 (60.5)
22 (42.3)
36 (62.1)
10 (47.6)
25 (37.9)
63 (58.3)
LVI
Identified
32 (74.4)
38 (73.1)
40 (69.0)
0.811
17 (81.0)
44 (66.7)
85 (78.7)
0.164
Not identified
11 (25.6)
14 (26.9)
18 (31.0)
4 (19.0)
22 (33.3)
23 (21.3)
Data are presented as n (%).Statistical significance at . BMI, body mass index; LVI, lymphovascular invasion. Other histologic subtypes included were invasive lobular carcinoma (ILC), ductal carcinoma in situ (DCIS), and mixed invasive ductal and lobular carcinoma.
