Central Obesity and Associated Factors among Adult Patients on Antiretroviral Therapy (ART) in Armed Force Comprehensive and Specialized Hospital, Addis Ababa, Ethiopia
Table 6
Multivariable binary logistic regression analysis to identify factors associated with central obesity among HIV patients who received ART at armed force comprehensive and specialized hospital, Ethiopia, 2018 (n = 353).
Variables
Category
COR (95% CI)
AOR (95% CI)
value
Sex
Female
7.72 (4.32, 13.8)
85.6 (20.1, 364.6)
<0.001
Male
1.00
1.00
Age (years)
0.99 (0.96, 1.02)
1.01 (0.96, 1.06)
0.610
Educational status
Illiterate
1.79 (0.74, 4.34)
1.31 (0.37, 4.57)
0.673
Primary/secondary
0.71 (0.41, 1.21)
0.48 (0.21, 1.07)
0.074
College and above
1.00
1.00
Occupational status
Housewife
1.00
1.00
Employer
0.32 (0.12, 0.85)
1.84 (0.36, 9.24)
0.46
Merchant
0.94 (0.17, 5.34)
18.8 (1.39, 255)
0.03
Pensioners
0.13 (0.05, 0.36)
1.31 (0.24, 7.10)
0.75
Unemployed
0.56 (0.13, 2.29)
2.13 (0.19, 25.5)
0.55
Marital status
Married
1.00
1.00
Never married
0.73 (0.33, 1.60)
1.67 (0.5, 5.58)
0.405
Widowed
3.00 (1.02, 8.85)
3.32 (0.59, 18.8)
0.175
Divorced
0.74 (0.37, 1.51)
0.31 (0.09, 1.04)
0.058
WHO clinical stage
Stage I
1.00
1.00
Stage II
2.76 (1.37, 5.56)
2.59 (0.80, 8.33)
0.110
Stage III
1.80 (0.91, 3.50)
2.20 (0.75, 6.42)
0.149
Stage IV
1.30 (0.63, 267)
1.09 (0.34, 3.51)
0.879
Duration on ART (months)
<59 months
1.00
1.00
60–107 months
0.86 (0.41, 1.84)
0.49 (0.14, 1.73)
0.269
>107 months
1.15 (0.58, 2.31)
0.35 (0.11, 1.15)
0.084
Type of regimen
AZT + 3TC + NPV
1.00
1.00
AZT + 3TC + EFV
3.63 (0.77, 17, 11)
8.73(1.33, 57.17)
0.024
TDF + 3TC + EFV
0.54 (0.28, 1.05)
0.45(0.16, 1.29)
0.137
TDF + 3TC + NPV
0.94 (0.35, 2.50)
0.51(0.10, 2.47)
0.401
ABC + 3TC + ATZ
0.18 (0.05, 0.67)
0.27(0.02, 2.90)
0.278
ABC + 3TC + ATV/r
0.35 (0.12, 0.98)
0.18(0.03, 0.94)
0.042
Baseline CD4 counts (cells/mm3)
<200
0.22 (0.03, 1.73)
0.4 (0.03, 6.04)
0.508
200–349
0.12 (0.01, 1.004
0.15 (0.01, 2.33)
0.175
350–499
0.15 (0.02, 1.35)
0.12 (0.007, 2.18)
0.152
>500
1.00
1.00
Current CD4 counts(cells/mm3)
<200
0.34 (0.16, 0.73)
0.03 (0.01, 0.160)
<0.001
200–349
0.53 (0.29, 0.99)
0.57 (0.20, 1.63)
0.294
350–499
1.15 (0.61, 2.18)
2.23 (0.84, 5.91)
0.106
>500
1.00
1.00
Current viral load (copies/ml)
≤1000 counts
1.00
1.00
≥1001 counts
0.50 (0.24, 1.04)
1.01 (0.26, 3.96)
0.987
Body mass index (BMI)
1.23 (1.15, 1.32)
3.50 (1.36, 3.89)
<0.001
Smoked cigarette
Yes
1.46 (0.48, 4.43)
1.32 (0.25, 7.12)
0.745
No
1.00
1.00
Consumed alcohol
Yes
0.86 (0.55, 1.34)
1.45 (0.66, 3.17)
0.351
No
1.00
1.00
Physical activity
Yes
1.00
1.00
0.86
No
0.81 (0.50, 1.29)
0.93 (0.399, 2.16)
Dietary diversity score
Diversified
1.05 (0.68, 1.61)
1.38 (0.65, 2.90)
0.40
Undiversified
1.00
1.00
Depression status
Normal
1.00
1.00
Abnormal
0.76 (0.43, 1.35)
0.58 (0.19, 1.74)
0.333
Total cholesterol (TC)
Normal
1.00
1.00
Abnormal
0.54 (0.35, 0.84)
0.39 (0.13, 1.22)
Low-density lipoprotein (LDL)
Normal
1.00
1.00
Abnormal
1.83 (1.15, 2.89)
1.43 (0.46, 4.45)
0.539
High-density lipoprotein (HDL)
Normal
1.00
1.00
Abnormal
1.62 (0.98, 2.69)
1.15 (0.46, 2.84)
0.763
Total triglyceride (TG)
Normal
1.00
1.00
Abnormal
1.41 (0.83, 2.40)
1.59 (0.66, 3.79)
0.298
Blood pressure (BP)
Normal
1.00
1.00
Abnormal
1.55 (0.95, 2.54)
2.53 (1.13, 5.67)
0.024
Fasting blood glucose (FBS)
1.002 (0.99, 1.01)
1.004 (0.99, 1.02)
0.514
value <0.05 (statistically significant association); 1.00: reference category. Hosmer and Lemeshow test ( value: 0.57).
