Journal of Obesity

Manifestations of Adipose Tissue Dysfunction


Publishing date
29 Mar 2013
Status
Published
Submission deadline
09 Nov 2012

Lead Editor

1University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA

2National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, MD 20892-2560, USA


Manifestations of Adipose Tissue Dysfunction

Description

We have abundant literature supporting a role of visceral obesity on glucose and lipid metabolism. However, the clinical implications of this research have been somewhat disappointing. Although BMI and waist circumference are widely used as measures of fat mass and distribution and have a role in predicting risk for type 2 diabetes and cardiovascular disease, their clinical value is evident only when combined with other metabolic abnormalities, such as those defining the metabolic syndrome. Metabolically healthy obese persons who do not need intervention for prevention of diabetes and cardiovascular disease are frequent in our clinics and, more importantly, metabolically unhealthy nonobese persons are also frequent and not easily identifiable as candidate for preventive treatment. This is particularly evident in ethnic minorities. Metabolic abnormalities, including insulin resistance, are more common in Asian Indians, African Americans, and Hispanics at lower BMI and waist circumferences, as compared to the European descent. It is now increasingly recognized that, at any level of BMI, adipose tissue function can more directly affect lipids and glucose metabolism. Identification of biomarkers of adipose tissue dysfunction may provide the much needed tools to identify a metabolic condition, which precedes and is a cause of chronic complications. Defining an adipose tissue dysfunction as a disease would be of value for regulatory agencies, pharmaceutical companies, and clinicians who could better focus prevention efforts.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the role of adipose tissue dysfunction in the pathogenesis of type 2 diabetes and cardiovascular disease, independently of obesity and fat distribution. We are particularly interested in articles describing candidate biomarkers of adipose tissue dysfunction, ethnic diversity in adipose tissue function, and mechanistic relationship between adipose tissue dysfunction and insulin resistance/metabolic syndrome. Potential topics include, but are not limited to:

  • Role of adiponectin and inflammatory markers in adipose tissue dysfunction
  • Role of adipose tissue dysfunction in hepatic steatosis
  • Role of adipose tissue inflammation in insulin resistance/metabolic syndrome
  • Adipose tissue mass distribution and function in various ethnic groups

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jobes/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jobes/adip/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 940275
  • - Editorial

Manifestations of Adipose Tissue Dysfunction

Nicola Abate | Anne E. Sumner | Manisha S. Chandalia
  • Special Issue
  • - Volume 2013
  • - Article ID 454285
  • - Clinical Study

Waist Circumference as Measure of Abdominal Fat Compartments

Scott M. Grundy | Ian J. Neeland | ... | Gloria Lena Vega
  • Special Issue
  • - Volume 2013
  • - Article ID 204094
  • - Review Article

Does Adipose Tissue Thermogenesis Play a Role in Metabolic Health?

Craig Porter | Elisabet Børsheim | Labros S. Sidossis
  • Special Issue
  • - Volume 2013
  • - Article ID 393192
  • - Review Article

Adipose Tissue Dysfunction in Nascent Metabolic Syndrome

Andrew A. Bremer | Ishwarlal Jialal
  • Special Issue
  • - Volume 2013
  • - Article ID 489187
  • - Review Article

Role of Subcutaneous Adipose Tissue in the Pathogenesis of Insulin Resistance

Pavankumar Patel | Nicola Abate
  • Special Issue
  • - Volume 2013
  • - Article ID 616193
  • - Review Article

The Role of the Immune System in Obesity and Insulin Resistance

Payal S. Patel | Eric D. Buras | Ashok Balasubramanyam
  • Special Issue
  • - Volume 2013
  • - Article ID 409679
  • - Clinical Study

Metabolic Risk Susceptibility in Men Is Partially Related to Adiponectin/Leptin Ratio

Gloria Lena Vega | Scott M. Grundy
  • Special Issue
  • - Volume 2013
  • - Article ID 312153
  • - Research Article

Maternal Docosahexaenoic Acid Increases Adiponectin and Normalizes IUGR-Induced Changes in Rat Adipose Deposition

Heidi N. Bagley | Yan Wang | ... | Lisa A. Joss-Moore
  • Special Issue
  • - Volume 2013
  • - Article ID 952916
  • - Review Article

The Role of Adipose Tissue in Insulin Resistance in Women of African Ancestry

Julia H. Goedecke | Naomi S. Levitt | ... | Dheshnie Keswell
Journal of Obesity
 Journal metrics
Acceptance rate28%
Submission to final decision92 days
Acceptance to publication47 days
CiteScore2.560
Impact Factor-
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