Table of Contents
Journal of Oral Diseases
Volume 2013, Article ID 401049, 11 pages
Review Article

Apoptosis and Its Significance in Oral Diseases: An Update

1Department of Oral Pathology and Microbiology, People’s Dental Academy, MIG, Block C, Flat No. 14, PCMS Campus, People’s Hospital, Bhopal, Madhya Pradesh 462037, India
2Department of Oral Pathology and Microbiology, People’s College of Dental Sciences and Research Center, Bhopal, Madhya Pradesh 462037, India
3Department of Oral Pathology and Microbiology, Coorg Institute of Dental Sciences, Virajpet, Karnataka 571218, India
4Department of Otolaryngology, All India Institute of Medical Sciences (AIIMS), Raipur, Chhattisgarh 492099, India
5Department of Oral Pathology and Microbiology, Rishiraj Dental College, Bhopal, Madhya Pradesh 462036, India

Received 24 September 2013; Accepted 8 December 2013

Academic Editor: Mitsuhiro Ohshima

Copyright © 2013 Megha Jain et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Apoptosis is a well defined mode of cell death which plays an imperative role in the development, regulation, and maintenance of the cell populations in multicellular organisms. Apoptosis is implicated in both health and diseases. Errors in apoptotic mechanisms have been allied to a wide range of pathologies including oral diseases. This review presents an update focused on the role and significance of apoptosis in various oral diseases ranging from reactive to benign and malignant pathologies.