Review Article

Saliva: A Cutting Edge in Diagnostic Procedures

Table 1

Salivary biomarkers in local and systemic disorders affecting the oral cavity [11, 20].

Dental biofilmInflammatoryCollagen breakdownBone remodellingSalivary steroid hormonesOral cancerAntibacterial substancesStress

Immunoglobulins (IgA, IgM, IgG) Beta-glucuronidaseAlpha2-macroglobulinAlkaline phosphataseCortisol M2BP Systemic C-reactive proteinCortisol
Mucins C-reactive proteinMMP-8osteoprotegerinTestosterone MRP14 Salivary chaperon H5p70Dopamine
Lysozyme IL-1 betaMMP-9osteocalcinDHEA-sCD 59Cystatin CNorepinephrine
LactoferrinIL-6Aspartate aminotransferaseSPARC/osteonectinProgesterone Profilin 1Alpha-amylaseEpinephrine
Histatin MIP-1alphaAlanine aminotransferaseRANKLEstradiol CatalaseCalprotectin
Peroxidase Tumor necrosis factor-alphaTIMPsBeta C-terminal type-I collagenAldosterone Protease inhibitors SLPI
C-telopeptide pyridinoline cross-links of type-I collagenDefensins
Proline-rich proteins