Table of Contents
Journal of Oral Diseases
Volume 2015 (2015), Article ID 854636, 10 pages
http://dx.doi.org/10.1155/2015/854636
Review Article

Malignant Transformation Rate in Patients Presenting Oral Epithelial Dysplasia: Systematic Review and Meta-Analysis

1Section of Population Oral Health, College of Dental Medicine, Columbia University, 622 W. 168th Street, Suite PH17-306R, New York, NY 10032, USA
2Department of Pediatric Dentistry, Henry M. Goldman School of Dental Medicine, Boston University, 100 E. Newton Street, Boston, MA 02118, USA

Received 4 August 2015; Revised 6 October 2015; Accepted 8 October 2015

Academic Editor: Yu Chao Chang

Copyright © 2015 Jaffer A. Shariff and Athanasios I. Zavras. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. National Cancer Institute—Oral Cancer, 2014, http://www.cancer.gov/types/head-and-neck/patient/oral-screening-pdq#section/_1.
  2. I. Ganly, S. Patel, and J. Shah, “Early stage squamous cell cancer of the oral tongue-clinicopathologic features affecting outcome,” Cancer, vol. 118, no. 1, pp. 101–111, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Jack, K. Lee, and A. Polonowita, “Dilemmas in managing oral dysplasia: a case report and literature review,” The New Zealand Medical Journal, vol. 122, no. 1291, pp. 89–98, 2009. View at Google Scholar · View at Scopus
  4. T. Nagao, N. Ikeda, H. Fukano, S. Hashimoto, K. Shimozato, and S. Warnakulasuriya, “Incidence rates for oral leukoplakia and lichen planus in a Japanese population,” Journal of Oral Pathology and Medicine, vol. 34, no. 9, pp. 532–539, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. D. F. Stroup, J. A. Berlin, S. C. Morton et al., “Meta-analysis of observational studies in epidemiology: a proposal for reporting,” Journal of the American Medical Association, vol. 283, no. 15, pp. 2008–2012, 2000. View at Publisher · View at Google Scholar · View at Scopus
  6. National Institute of Health and Department of Health and Human Services, “Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies,” 2015l, https://www.nhlbi.nih.gov/health-pro/guidelines/in-develop/cardiovascular-risk-reduction/tools/cohort.
  7. P. C. Gupta, F. S. Mehta, D. K. Daftary et al., “Incidence rates of oral cancer and natural history of oral precancerous lesions in a 10-year follow-up study of Indian villagers,” Community Dentistry and Oral Epidemiology, vol. 8, no. 6, pp. 287–333, 1980. View at Publisher · View at Google Scholar · View at Scopus
  8. S.-S. Hsue, W.-C. Wang, C.-H. Chen, C.-C. Lin, Y.-K. Chen, and L.-M. Lin, “Malignant transformation in 1458 patients with potentially malignant oral mucosal disorders: a follow-up study based in a Taiwanese hospital,” Journal of Oral Pathology and Medicine, vol. 36, no. 1, pp. 25–29, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. P.-S. Ho, P.-L. Chen, S. Warnakulasuriya, T.-Y. Shieh, Y.-K. Chen, and I.-Y. Huang, “Malignant transformation of oral potentially malignant disorders in males: a retrospective cohort study,” BMC Cancer, vol. 9, article 260, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. W. Liu, Z.-X. Bao, L.-J. Shi, G.-Y. Tang, and Z.-T. Zhou, “Malignant transformation of oral epithelial dysplasia: clinicopathological risk factors and outcome analysis in a retrospective cohort of 138 cases,” Histopathology, vol. 59, no. 4, pp. 733–740, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Holmstrup, P. Vedtofte, J. Reibel, and K. Stoltze, “Long-term treatment outcome of oral premalignant lesions,” Oral Oncology, vol. 42, no. 5, pp. 461–474, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. C. G. Cowan, T. A. Gregg, S. S. Napier, S. M. McKenna, and F. Kee, “Potentially malignant oral lesions in Northern Ireland: a 20-year population-based perspective of malignant transformation,” Oral Diseases, vol. 7, no. 1, pp. 18–24, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Bánóczy and A. Csiba, “Occurrence of epithelial dysplasia in oral leukoplakia. Analysis and follow-up study of 12 cases,” Oral Surgery, Oral Medicine, and Oral Pathology, vol. 42, no. 6, pp. 766–774, 1976. View at Google Scholar
  14. M. W. Ho, J. M. Risk, J. A. Woolgar et al., “The clinical determinants of malignant transformation in oral epithelial dysplasia,” Oral Oncology, vol. 48, no. 10, pp. 969–976, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Warnakulasuriya, T. Kovacevic, P. Madden et al., “Factors predicting malignant transformation in oral potentially malignant disorders among patients accrued over a 10-year period in South East England,” Journal of Oral Pathology and Medicine, vol. 40, no. 9, pp. 677–683, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. P. G. Arduino, A. Surace, M. Carbone et al., “Outcome of oral dysplasia: a retrospective hospital-based study of 207 patients with a long follow-up,” Journal of Oral Pathology and Medicine, vol. 38, no. 6, pp. 540–544, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. H. H. Mincer, S. A. Coleman, and K. P. Hopkins, “Observations on the clinical characteristics of oral lesions showing histologic epithelial dysplasia,” Oral Surgery, Oral Medicine, Oral Pathology, vol. 33, no. 3, pp. 389–399, 1972. View at Publisher · View at Google Scholar · View at Scopus
  18. H. Lumerman, P. Freedman, and S. Kerpel, “Oral epithelial dysplasia and the development of invasive squamous cell carcinoma,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and, vol. 79, no. 3, pp. 321–329, 1995. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Sperandio, A. L. Brown, C. Lock et al., “Predictive value of dysplasia grading and DNA ploidy in malignant transformation of oral potentially malignant disorders,” Cancer Prevention Research, vol. 6, no. 8, pp. 822–831, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. F. Dost, K. Lê Cao, P. J. Ford, C. Ades, and C. S. Farah, “Malignant transformation of oral epithelial dysplasia: a real-world evaluation of histopathologic grading,” Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol. 117, no. 3, pp. 343–352, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. G. Bradley, E. W. Odell, S. Raphael et al., “Abnormal DNA content in oral epithelial dysplasia is associated with increased risk of progression to carcinoma,” British Journal of Cancer, vol. 103, no. 9, pp. 1432–1442, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. L. Zhang, C. F. Poh, M. Williams et al., “Loss of heterozygosity (LOH) profiles—validated risk predictors for progression to oral cancer,” Cancer Prevention Research, vol. 5, no. 9, pp. 1081–1089, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. H. M. Mehanna, T. Rattay, J. Smith, and C. C. McConkey, “Treatment and follow-up of oral dysplasia—a systematic review and meta-analysis,” Head and Neck, vol. 31, no. 12, pp. 1600–1609, 2009. View at Publisher · View at Google Scholar · View at Scopus