¹⁸F-FDG PET-CT in the Management of Patients Receiving Definitive Radiotherapy for Malignancies of the Head and Neck

Table 1

Diagnostic performance of ¹⁸F-FDG PET-CT in the identification of residual/recurrent malignancy or second primary cancers following intensity modulated radiation therapy (IMRT) ± combined chemotherapy for treatment of primary cancers of the head and neck, by site.

	TP	FP	FN	TN	Sensitivity	Specificity	PPV	NPV	Accuracy
Overall
332	58 (17.5%)	12 (3.6%)	0 (0%)	262 (78.9%)	100.0%	95.6%	82.9%	100.0%	96.4%
Nasopharynx
33	6 (18.2%)	0 (0%)	0 (0%)	27 (81.8%)	100.0%	100.0%	100.0%	100.0%	100.0%
Oropharynx
161	26 (16.1%)	6 (3.8%)	0 (0%)	129 (80.1%)	100.0%	95.6%	81.3%	100.0%	96.3%
Oral cavity
93	16 (17.2%)	5 (5.4%)	0 (0%)	72 (77.4%)	100.0%	93.5%	76.2%	100.0%	94.6%
Larynx and hypopharynx
18	3 (16.7%)	0 (0%)	0 (0%)	15 (83.3%)	100.0%	100.0%	100.0%	100.0%	100.0%
Salivary gland
27	7 (25.9%)	1 (3.7%)	0 (0%)	19 (70.4%)	100.0%	95.0%	87.5%	100.0%	96.3%