Journal of Ophthalmology / 2009 / Article / Tab 3

Clinical Study

Association of Lumican Gene with Susceptibility to Pathological Myopia in the Northern Han Ethnic Chinese

Table 3

The frequencies of genotype, allele and the P value of HWE.

GeneSNP (mutation, location)GroupGenotype (%)P valueHWEAllele (%)P value

lumicanRs3759223 (C→T, 5 RR)C/CC/TT/T.000CT.000
Case0.0640.3300.6060.5270.2290.771
Control0.50.3560.1440.0780.6780.322
Rs17853500 (T→C, Exon 2)T/TT/CC/C.000TC.000
Case0.4790.3620.1600.0590.6600.340
Control0.8330.1670.0000.3880.9170.083
Rs11105988 (A→T, intron2)A/AA/TT/T.997AT.992
Case0.7980.1700.0320.0870.8330.117
Control0.8000.1670.0330.0700.8330.117
Rs17018718 (G→A, intron2)G/GG/AA/A.996AG.966
Case0.8300.1490.0210.1750.0960.904
Control0.8330.1440.0220.1400.0940.906

DecorinRs7441 (T→C, 3 UTR)T/TC/TC/C.033CT.004
Case0.0530.2230.7230.0670.8350.165
Control0.1220.3330.5440.0730.7110.289

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