Association of Lumican Gene with Susceptibility to Pathological Myopia in the Northern Han Ethnic Chinese

Table 3

The frequencies of genotype, allele and the P value of HWE.

Gene	SNP (mutation, location)	Group	Genotype (%)			P value	HWE	Allele (%)		P value
lumican	Rs3759223 (C→T, 5^′RR)		C/C	C/T	T/T	.000		C	T	.000
		Case	0.064	0.330	0.606		0.527	0.229	0.771
		Control	0.5	0.356	0.144		0.078	0.678	0.322
	Rs17853500 (T→C, Exon 2)		T/T	T/C	C/C	.000		T	C	.000
		Case	0.479	0.362	0.160		0.059	0.660	0.340
		Control	0.833	0.167	0.000		0.388	0.917	0.083
	Rs11105988 (A→T, intron2)		A/A	A/T	T/T	.997		A	T	.992
		Case	0.798	0.170	0.032		0.087	0.833	0.117
		Control	0.800	0.167	0.033		0.070	0.833	0.117
	Rs17018718 (G→A, intron2)		G/G	G/A	A/A	.996		A	G	.966
		Case	0.830	0.149	0.021		0.175	0.096	0.904
		Control	0.833	0.144	0.022		0.140	0.094	0.906
Decorin	Rs7441 (T→C, 3^UTR)		T/T	C/T	C/C	.033		C	T	.004
		Case	0.053	0.223	0.723		0.067	0.835	0.165
		Control	0.122	0.333	0.544		0.073	0.711	0.289