Clinical Study

Pegaptanib Sodium versus Pegaptanib Sodium Combined with Macular Laser Photocoagulation or Laser Alone for Diabetic Macular Edema

Table 1

Patients’ baseline characteristics. ETDRS: early treatment diabetic retinopathy study, DME: diabetic macular edema, CMT: central macular thickness, BCVA: best corrected visual acuity.

Pegaptanib Sodium injection groupCombined treatment groupMacular Laser Photocoagulation group

Total N° of eyes131215
N° of Male patients8710
Mean age65,8 ± 6,1 (95% CI = 62.3, 69.2)62,4 ± 5,5 (95% CI = 59.2, 65.6)67 ± 8.6 (95% CI = 62.6, 71.6)
Duration of diabetes13.7 yrs (mean)12,8 yrs (mean)14,9 yrs (mean)
Diffuse DME7 eyes7 eyes9 eyes
Cystoid DME6 eyes5 eyes6 eyes
Mean CMT (μm)509 ± 125,6 (95% CI = 438.6, 579.4)420,3 ± 116,3 (95% CI = 352.3, 488.2)335 ± 91,1 (95% CI = 287.4, 382.6)
Mean BCVA (LogMAR)0,7 ± 0,4 (95% CI = 0.5, 1)0,3 ± 0,3 (95% CI = 0.1, 0.4)0.3 ± 0.3 (95% CI = 0.1, 0.4)