Inhibition of Methylglyoxal-Mediated Protein Modification in Glyoxalase I Overexpressing Mouse Lenses

Figure 5

Promotion of pentosidine synthesis by Glo I overexpression. Wt and Glo I lens homogenates (5 mg/ml) were incubated with 5 mM ribose for 7 days and analyzed by HPLC for pentosidine. The results are the mean $\pm$ SD from 3 experiments. (${}^{*}P<.0001$).