Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas

Table 3

Regions with strongest imputation-inferred associations ($P<.0001$) using estimated allelic dosage under an adjusted additive genetic model.

Location	SNP with best $P$-value within this region	${\text{Position}}^{*}$	Best $P$-${\text{value}}^{\S }$	# of top SNPs within this region	Nearest $\text{gen}{\text{e}}^{*}$
6p11-12	rs6909083	54290262	$1.80E-05$	7	TINAG
6q22	rs17083119	121443809	$2.76E-05$	4	C6orf170
1q23	rs1033465	171254353	$4.50E-05$	2	TNFSF18
1p13	rs11583330	109925036	$5.35E-05$	1	GNAI3
1q42	rs3014267	225619540	$6.58E-05$	1	CDC42BPA
15q13	rs11635920	30999949	$7.18E-05$	4	FMN1, GREM1
2q35-36	rs6726798	219009099	$8.66E-05$	1	VIL1
10q21	rs11812882	59712631	$8.85E-05$	1	ZCD1
2q35	rs1106412	219023301	$8.91E-05$	1	USP37
3p24	rs11927173	23200198	$9.39E-05$	2	UBE2E2
8q22	rs3098241	104494480	$9.72E-05$	2	SLC25A32

${}^{*}$Affymetrix NetAffx annotation build 25, NCBI genome build 36.1
${}^{\S }P$-value of logistic regression under additive genetic model, adjusted for age, gender, diabetes duration, and HbA1C level.