Journal of Ophthalmology / 2011 / Article / Tab 2

Clinical Study

Comparison of Photopic Negative Response of Full-Field and Focal Electroretinograms in Detecting Glaucomatous Eyes

Table 2

Sensitivity and specificity of the PhNR amplitude to discriminate glaucomatous eyes.

Sensitivity (95%CI)Specificity (95%CI)Cut-off value ( V)

Early

Full-field ERG38.1 (23.6–54.4)92.3 (79.1–98.3)22
Focal ERG
 Center69.1 (52.9–82.4)95.2 (83.8–99.3)0.7
 Sup/temp63.4 (46.9–77.9)97.6 (87.1–99.6)0.5
 Inf/temp56.1 (46.9–77.9)95.2 (83.8–99.3)0.7
 Combined88.1 (74.4–96.0)90.5 (87.7–99.6)

Intermediate

Full-field ERG59.3 (38.8–77.6)92.3 (79.1–98.3)22
Focal ERG
 Center64.3 (44.1–81.3)95.2 (83.8–99.3)0.7
 Sup/temp75.0 (55.1–89.3)97.6 (87.1–99.6)0.5
 Inf/temp67.9 (47.7–84.1)95.2 (83.8–99.3)0.7
 Combined92.9 (87.7–99.6)90.5 (87.7–99.6)

Advanced

Full-field ERG66.7 (48.2–82.0)92.3 (79.1–98.3)22
Focal ERG
 Center88.2 (72.5–96.6)95.2 (83.8–99.3)0.7
 Sup/temp90.9 (75.6–98.0)97.6 (87.1–99.6)0.5
 Inf/temp90.9 (75.6–98.0)95.2 (83.8–99.3)0.7
 Combined97.1 (87.7–99.6)90.5 (87.7–99.6)

PhNR: photopic negative response; CI: confidence interval; sup/temp: superior/temporal; inf/temp: inferior/temporal.

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