Clinical Study
Comparison of Photopic Negative Response of Full-Field and Focal Electroretinograms in Detecting Glaucomatous Eyes
Table 2
Sensitivity and specificity of the PhNR amplitude to discriminate glaucomatous eyes.
| | Sensitivity (95%CI) | Specificity (95%CI) | Cut-off value (V) |
| | Early | | | |
| | Full-field ERG | 38.1 (23.6–54.4) | 92.3 (79.1–98.3) | 22 | | Focal ERG | | | | | Center | 69.1 (52.9–82.4) | 95.2 (83.8–99.3) | 0.7 | | Sup/temp | 63.4 (46.9–77.9) | 97.6 (87.1–99.6) | 0.5 | | Inf/temp | 56.1 (46.9–77.9) | 95.2 (83.8–99.3) | 0.7 | | Combined | 88.1 (74.4–96.0) | 90.5 (87.7–99.6) | |
| | Intermediate | | | |
| | Full-field ERG | 59.3 (38.8–77.6) | 92.3 (79.1–98.3) | 22 | | Focal ERG | | | | | Center | 64.3 (44.1–81.3) | 95.2 (83.8–99.3) | 0.7 | | Sup/temp | 75.0 (55.1–89.3) | 97.6 (87.1–99.6) | 0.5 | | Inf/temp | 67.9 (47.7–84.1) | 95.2 (83.8–99.3) | 0.7 | | Combined | 92.9 (87.7–99.6) | 90.5 (87.7–99.6) | |
| | Advanced | | | |
| | Full-field ERG | 66.7 (48.2–82.0) | 92.3 (79.1–98.3) | 22 | | Focal ERG | | | | | Center | 88.2 (72.5–96.6) | 95.2 (83.8–99.3) | 0.7 | | Sup/temp | 90.9 (75.6–98.0) | 97.6 (87.1–99.6) | 0.5 | | Inf/temp | 90.9 (75.6–98.0) | 95.2 (83.8–99.3) | 0.7 | | Combined | 97.1 (87.7–99.6) | 90.5 (87.7–99.6) | |
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PhNR: photopic negative response; CI: confidence interval; sup/temp: superior/temporal; inf/temp: inferior/temporal.
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